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In a 72-week study enrolling 3,172 overweight adults, the highest dose of orforglipron (36 mg) caused 12.4% weight loss
doi: 10.1016/j.yjmcc.2014.09.022 260
Tirzepatide enhances the effects of GLP-1 and GIP
This mechanism is highly effective for weight loss, but it can trigger nausea as your digestive system adjusts
Our calculator uses weight loss curves derived from the STEP-1 and SURMOUNT-1 clinical trials combined with your personal data (current weight, height, age, and target weight) to project a personalized week-by-week weight loss timeline
Your actual titration schedule may vary based on your health history and response to treatment
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