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Tsai CJ, Leitzmann MF, Hu FB, Willett WC, Giovannucci EL

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Contraindications : Avoid with MAOIs, SSRIs, or if pregnant/breastfeeding

Additional support, like sleep hygiene education, mindfulness techniques, and cognitive behavioral strategies, can also be delivered through video sessions or digital modules to help manage stress, which can worsen PCOS symptoms

Supportive strategies include: Building media literacy around weight-loss headlines and wellness trends

UPP1 facilitates the conversion of 5-FU into its active compounds, thereby enhancing its inhibitory effect on thymidylate synthase