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Limitations: It has relatively low sensitivity and is not suitable for samples with strong antibacterial properties
Neurodegenerative diseases: oxidative stress meets neuroinflammation Role of oxidative stress and neuroinflammation in neurodegenerative diseases Neurodegenerative diseases share common features such as oxidative damage, neuroinflammation, autophagy dysfunction, protein aggregation, and mitochondrial defects [2, 55]
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During the HMs-induced ROS scavenging system the GSH is changed to its oxidized form (GSSG) which is one of the key processes of the redox signaling process (Figure 3)
The diagnosis of 5-oxoprolinase deficiency is established by: Low activity of 5-oxoprolinase in nucleated cells such as leukocytes or cultured skin fibroblasts (5-oxoprolinase is not present in erythrocytes)
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