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The immune cells in these patients are dealing with such an extreme, unrelenting burden of oxidative stress and mitochondrial lipid damage that they have frantically ramped up their own internal glutathione production in a desperate attempt to survive
The CPT1A form is mainly found in the liver, while the CPT1B form is predominantly found in the heart and skeletal muscles
ROC curves were generated from model predictions, and diagnostic utility was quantified using the area under the curve (AUC)
Ahluwalia et al
Doi: Galati DF, Sullivan KD, Pham AT, Espinosa JM, Pearson CG (2018) Trisomy 21 Represses Cilia Formation and Function
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