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Studies have shown that although many cells express APEX2 at low levels, it exhibits improved thermal stability and higher biotinylation activity compared to APEX

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Activation of GLP1R in the brain by GLP-1RA represents an effective intervention against neuroinflammation: it inhibits microgliosis and astrogliosis, suppresses NFB and inflammasome activity, reduces peripheral immune cell recruitment, protects against oxidative stress, and promotes neuroprotective signalling (120)

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In our study we have focused overall changes taking place in lungs over short term (2h-4h) to long term (16-48h) HH