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Structurally identical to native exendin-4, exenatide is a chemically synthesized peptide with clinical applications in the management of type 2 diabetes

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doi: 10.1210/endo.139.9.6288 95 JonesIOwensDRLuzioSDHayesTM

Addition of the ISR agonist Sephin1 to cultured human OLmaintained under control conditions or exposed to ongoing metabolic stressreduced process outgrowth 42 , suggesting that the ISR regulates the protein synthesis machinery required for OL process outgrowth and maintenance

This comprehensive approach typically includes health and lifestyle modifications, dietary adjustments, exercise, and medication when appropriate

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