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Oxidative stress in CKD Oxidative stress arises when there is an imbalance between free radical production and antioxidant defense
doi: 10.1007/s11064-023-04000-z 2
GIP is also implicated in nausea attenuation, which may be why GLP-1/GIP dual agonists like tirzepatide have a slightly better GI tolerability profile than pure GLP-1 agonists
They do work, but some people stop taking them due to side effects, which include nausea, vomiting, diarrhea, or constipation
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