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Effects of topical creams containing vitamin C, a copper-binding peptide cream, and melatonin compared with tretinoin on the ultrastructure of normal skin
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[16] [18] Ascorbic acid crosses the placenta and is excreted in breast milk
While benign, the urinary discolouration may interfere with colorimetric laboratory analyses, and may impede intermittent haemodialysis due to the pigment distribution across the dialysate membrane triggering colorimetric blood leak sensors
Funding This study was partially supported by Fundao Carlos Chagas Filho de Amparo Pesquisa do Estado do Rio de Janeiro (FAPERJ - E-26/201.289/2022), Brazil
This pharmacologic property distinguishes it from small-molecule therapeutics where hepatic impairment dramatically alters drug-drug interaction profiles
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