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doi: 10.1016/j.eclinm.2024.103012, 172

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Adult mice with skeletal muscle-specific LONP1 deletion also exhibit osteoporosis-like phenotypes, including bone loss and mechanical fragility

This mechanism is well-documented: a peer-reviewed review in Drugs evaluating Sermorelins use in the diagnosis and treatment of growth hormone deficiency confirms it works by stimulating endogenous pituitary GH release through the GHRH receptor