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Morbidity improvements are generally lower than mortality improvements due to a higher proportion of morbidity incidence (in a critical illness product) being caused by cancers (where the relative risks of incidence by BMI are lower), compared to mortality, with a higher proportion of deaths caused by CVD (where the relative risks by BMI are higher)
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10.2165/00003495-200767040-00007 109 MakrilakisK
Diabetes itself is associated with increased risk of various cancers, potentially through mechanisms involving chronic inflammation, insulin resistance, and metabolic dysregulation [11, 12]
The analysis module on Halo was used to extract the cytoplasmic positivity for Melan-A, CD8, CD4, PD-L1, F4/80 and nuclear positivity of FOXP3 on all samples, stratifying the results on the basis of areas (that is, central tumour, tumour periphery and non-neoplastic/peritumoural)
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