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Grce la technologie liposomale, le glutathion rduit est encapsul dans des vsicules de phospholipides de tournesol qui imitent la structure des membranes cellulaires
10.1038/nature12040 263 SousaC
Temperature extremesboth hot and coldcan damage the active ingredients in the medication
However, many reported GSH-responsive systems demonstrate incomplete drug release under physiological intracellular GSH levels (110 mM), suggesting an overestimation of redox sensitivity in vitro
But with a 2mg/mL concentration (5mL of water added), that same 4mg dose requires 2.0mL of liquid, which is an entire insulin syringe worth and creates a large, uncomfortable injection volume
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