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No receptor fatigue was observed

When the DAO enzyme fails to function correctly, breaking down histamine naturally becomes difficult, leading to an allergic reaction called histamine intolerance

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Additional information Peer review information Nature Metabolism thanks Dominique Langin and the other, anonymous reviewers for their contribution to the peer review of this work

Therefore, in one person, it may trigger excess histamine release, causing the symptoms of histamine intolerance, while in another person, it may not cause any symptoms

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