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Specialized industries are defined as those within a specific industry category with a location quotient exceeding 1.25, and the quotients of specialized industries are recalculated using the number of employees working for the specialized industries in the region(Lee and Lim, 2021)

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Since BCRP is highly expressed on the apical membrane of enterocytes and effluxing substrates back into the lumen, it has been noted to play an important role as a detoxification efflux transporter and limiting drug absorption in the GIT (Zaher et al

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