Developed by Eli Lilly under the compound code LY3437943, retatrutide simultaneously activates GLP-1, GIP, and glucagon receptors a mechanism that distinguishes it from currently approved agents such as semaglutide and tirzepatide
This hormone helps control appetite, manage blood sugar, and slow the movement of food through the stomach
It updated the product insert for all GLP-1 receptor-agonist medications, advising that patients should be monitored for depression, suicidal ideation, and changes in mood or behaviour, and that the benefits and risks for patients with current or past suicidal thoughts or behaviours should be considered before prescribing or continuing the drug
Researchers followed people who had prediabetes and overweight or obesity for three years
But a secret shopper study published in JAMA on July 6 found that telehealth GLP-1 vendors often dont require a patient to talk with a clinician before getting a prescription, raising concerns about safety and oversight
Mental Health Issues: Magnesium deficiency has been linked to mood disorders like depression and anxiety