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Gene expression breadth: Pickart and Margolina (2018) analyzed GHK against the Connectivity Map database and reported effects on gene sets associated with inflammation, DNA repair, ubiquitin-proteasome pathways, and mitochondrial function, spanning more than 4,000 genes in their analysis

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GHK was first discovered in 1973 by the noted peptide researcher Dr

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GLP-1RAs also exert anti-arrhythmic effects via reducing calcium leak from the sarcoplasmic reticulum in ventricular arrhythmia, which has the potential to decrease phosphorylation of the type 2 ryanodine receptor (RyR2) and alleviate the activity of CaMK-II [77]

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