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It also attacks the cell that causes autoimmune conditions by reducing free radicals

It is approved to reduce risk of sustained eGFR decline, end stage kidney disease and cardiovascular death in adults with chronic kidney disease

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Although certain trials demonstrate benefits in insulin sensitivity and hepatic steatosis, others report neutral outcomes

In diet-induced obesity models, this inhibition has been observed to reduce white fat accumulation and promote lipolysis, effectively reprogramming metabolic pathways toward enhanced energy expenditure