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Despite its therapeutic promise, more studies are needed to confirm its efficacy and safety for clinical use

These landmark studies, required by regulatory authorities including the EMA and MHRA , have provided reassuring evidence about the cardiovascular safety profile of this drug class

Jiang L, Li J, Tang B, Guo J

Dosing schedule: Week 1-4: 2.5 mg (starting dose) Week 5-8: 5 mg Week 9-12: 7.5 mg Maintenance Dose: 10 mg, 12.5 mg, or 15 mg (as prescribed) Tip: Stick to a consistent weekly schedule to maintain effectiveness

Both medications require several months to reach their peak effects