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Constipation and stomach ache were reported more frequently in the active group (10%) compared to the placebo group (3%)
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Theres also disulfiram, which causes people to feel violently ill if they consume alcohol while on it, and acamprosate, which is believed to treat the imbalance of neurotransmitters in the brain following chronic alcohol consumption and can help reduce the brains dependence on alcohol, though the exact mechanism is still not fully understood
The company noted the candidate's competitive safety profile and sustained efficacy over 28 weeks, with plans to advance it into Phase 3 trials in 2026
