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The trial included 60 adult participants (mean age approximately 49) who had clinical follow-up with labs every 2 months for up to 2 years, with some withdrawing early due to spontaneous remission, indication for definitive therapy (e.g., thyroidectomy or radioiodine), or an intolerance to the treatment
Employers who invest in evidence-based obesity treatment can improve recruitment and retention, support both physical and mental well-being, and demonstrate a genuine commitment to long-term employee well-being
Statistical analysis The summary effect of GLP-1RAs on the endpoint of MALE was estimated
For testosterone, data imply support for Leydig cell function and steroid output under stress conditions
Physicians strongly recommend that patients follow a healthy diet and take regular exercise while using tirzepatide to enhance treatment outcomes