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Inflammation and neuroprotection in traumatic brain injury
( d ) Cells were treated with the IDH1 (IDH1i) and olaparib (Olap) or cisplatin (Cis) alone or combined (n = 4 technical replicates representative from independent experiments)
(PubMed) Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM
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In the Phase 3 obesity cohort, 4 mg produced about 19% weight loss at 80 weeks, with dropout no higher than placebo
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