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New insights into the role of lipoprotein (a)-associated lipoprotein-associated phospholipase A2 in atherosclerosis and cardiovascular disease
Lifestyle changes Its no secret that lifestyle changes play a significant role in weight loss
Gastric motility and the gut-brain axis Slowed gastric emptying is a direct peripheral effect of GLP-1 receptor activation on the vagus nerve and enteric nervous system
The trial demonstrated a 20% reduction in the primary composite endpoint of cardiovascular death, nonfatal heart attack, or nonfatal stroke (hazard ratio 0.80, 95% CI 0.72-0.90)
Multi-approach is used for efficacy and sustainability
Financial support and sponsorship This work was supported by National Institutes of Health grants R01 AG057381 (Ladiges and Darvas, co-PI's) and R01 AG057381 (Ladiges PI)
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