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While there is limited evidence of direct impairment in taste perception, one trial did observe that individuals taking GLP-1 RAs scored lower on both taste and smell assessments (Waterless Empirical Taste Test (WETT) and University of Pennsylvania Smell Identification Test (UPSIT), respectively

Patients should be educated about red-flag features that require urgent assessment

A concern that can be plausibly doubted or denied carries no legal liability, whereas one that gives rise to serious consideration leaves the door wide open to lawsuits

Effects of SGLT2 inhibitors on ion homeostasis and oxidative stress associated mechanisms in heart failure

The conversion chart between the two medications helps ensure appropriate dosing during switches

Diabetes mortality and trends before 25 years of age: an analysis of the global burden of disease study 2019