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Finally, set realistic expectations: some degree of adjustment is normal when starting these medications, and many patients find that energy levels improve as their bodies adapt to the new metabolic state and side effects diminish, typically within the first 48 weeks of treatment

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Taken together, evidence from neuroscience, human research, and clinical practice suggests meaningful overlap between obesity and addiction-related mechanisms. Leggio says that his lab has long been interested in how gut-brain neuroendocrine pathways may influence alcohol use disorder (AUD)

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