Older people might experience decreased liver and kidney function, which could influence how their bodies process and eliminate methylcobalamin
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PMC11862975
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Although sensory ganglia are understood to be the primary source of virus establishing latency, recent studies using a modified ex vivo tissue explant reactivation assay have found that 80% of brainstem explants display viral reactivation following latent infection with KOS or McKrae HSV-1 viruses, indicating that the CNS can also be an effective source of infectious HSV-1 from which the virus reactivates (Chen et al., 2006)
Carrasco P, Querol A, del Olmo M (2001) Analysis of the stress resistance of commercial wine yeast strains