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Well, I think thats all of our questions that we have here today
In both MES-1 and MES-2 most of the upregulated in hLMNA-R482L DEGs, such as Mgp, Ogn, Spp1, Igfbp5, Col1a1, Col6a1, Ptn, are related to connective tissue development, ossification, biomineralization, negative regulation of cell migration and locomotion (Fig
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Gnoni, G
The result, in the landmark STEP clinical trials published in The New England Journal of Medicine , was an average body weight reduction of approximately 15% over 68 weeks a level of efficacy previously only seen with bariatric surgery
Scheme 17
