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However, this effect may be due to the large amount of cystine provided in the control conditions (208 M), as reduction of cystine levels in the medium did not impair growth but abolished intracellular cysteine and cystine levels (Extended Data Fig

So far, this function has likely been underestimated compared to the other documented roles of GSTs

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pylori infection and resistance to apoptosis

Improved Glucose and Lipid Metabolism : Experimental studies demonstrate that suppression of NNMT activity with 5-Amino-1MQ correlates with improved glucose tolerance and reduced hepatic lipid accumulation

Fertility effects are case specific