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Additionally, the precise spatiotemporal crosstalk between ferroptosis, apoptosis, and necroptosis adds a layer of complexity that confounds the design of specific interventions

[DOI] [PubMed] Cover C, Mansouri A, Knight TR, Bajt ML, Lemasters JJ, Pessayre D, et al

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A 2013 prospective study by Ornish and colleagues (N=35) published in The Lancet Oncology demonstrated that comprehensive lifestyle changes (plant-based diet, moderate exercise, stress management, social support) increased telomerase activity by 29% over 5 years 11

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Ginkgolide B, a major component of Ginkgo biloba , protects against ototoxicity caused by cisplatin in vitro and in vivo by decreasing ROS production through the reduction of NOX2 expression and the enhancement of activity via the Akt/Nrf-2/HO-1 pathway, mitochondrial apoptosis is inhibited (Ma et al