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Resistance training and adequate protein intake (1.0-1.6 g/kg/day) are far more effective strategies for muscle preservation during weight loss

Proc Natl Acad Sci U S A 2020;117:29959-29967

The TGA, which regulates drugs in Australia, has called for Trulicitys label to be updated to reflect this finding

Metformin has been reported to protect human islets against lipotoxicity 16

To check your coverage, follow these steps: Review your plan's drug formulary: Look for your prescribed GLP-1 and check its coverage tier and any restrictions

This triple mechanism creates a combined metabolic effect that is broader than current single or dual pathway weight loss medications