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The dosage per the HCPCS descriptor is the minimum dosage and is considered 1 unit

Patients should be aware that: No licensed combination product exists in the UK Any combination use would be considered experimental and is not supported by current evidence Clinical decisions must be guided by a qualified healthcare professional with access to current trial data Clinical Evidence and Trial Data Available to UK Patients Retatrutide Phase 2 data showed approximately 24% mean body weight reduction at the highest dose over 48 weeks, but no published trial data exist for the specific cagrilintideretatrutide combination

Cost considerations become significant at these higher doses

110(3):774 to 780

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Drug combinations: a strategy to extend the life of antibiotics in the 21st century