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In GHK-Cu, it denotes that the tripeptide glycyl-L-histidyl-L-lysine (GHK) is bound to a copper(II) ion, forming the copper-peptide complex researchers study the Cu specifically distinguishes the copper-bound complex from the standalone GHK peptide, which research has shown behaves differently without the copper ion attached

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The FDAs accelerated approval was backed by the eNRGy study, which touted a 40% and 33% overall response rate in patients with pancreatic adenocarcinoma and NSCLC, respectively

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