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Carnitines role in brain health: Besides fertility, carnitine is implicated in brain plasticity and cognitive functions, with acetylcarnitine influencing gene expression through histone acetylation
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Notably, GLP-1R is abundantly expressed in various brain regions, including the hypothalamus, cortex, and hippocampus, as well as peripheral nervous tissues [10]
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This is the mechanism behind Ozempic, approved for type 2 diabetes, and Wegovy, approved for chronic weight management
To evaluate aging, the researchers relied on several "epigenetic clocks." These tools estimate biological age by measuring DNA methylation, a pattern of chemical tags that influences how genes are switched on or off without changing the DNA sequence itself
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