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Main aim The study hypotheses were that (1) diurnal changes occur in the entire spine as well as (2) IVDs of weightlifters (WL) have decreased baseline T2-mapping values (possibly water content) in the morning and (3) increased diurnal changes throughout the day

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[9] Mechanistically, cagrilintide is thought to reduce body weight primarily by acting on both homeostatic appetite centers (the physiological hunger/fullness system) and hedonic ones (the reward-driven side of eating), lowering food intake without directly forcing energy expenditure up