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Results FreSHtracer-isolated MSCs with high GSH levels show enhanced stem cell functions We first investigated whether FreSHtracer could be used to monitor cellular levels of GSH in living hES-MSCs sorted by flow cytometry according to the F 510/580 ratio
The cells treated with Sp showed slight enhancement in levels of GSH (~1.2 fold), together with minor alterations in GSSG levels, compared to untreated samples which exhibited higher GSSG content, thus indicating efficient recycling of GSSG to GSH (Fig
The three phases are activation in weeks 14, remodeling in weeks 58, and maintenance in weeks 912
Bi W, Deng JM, Zhang Z, Behringer RR, de Crombrugghe B
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