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Do I need to see an endocrinologist before starting tirzepatide if I have Hashimotos? Not necessarily if your Hashimotos is well-controlled on stable levothyroxine with TSH consistently in normal range for six months or longer, your primary care physician or weight loss prescriber can initiate tirzepatide with appropriate thyroid monitoring

These tend to be most noticeable at the start or after dose increases

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However, more serious side effects have also been reported

Plunger becoming stiff or sticky After several days in storage, you might find that the syringe plunger resists smooth movement