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Novo Nordisk continues to promote and sell these products without any warning or discussion in their label regarding a risk of permanent vision loss. According to Gold, lawsuits allege that Novo Nordisk failed to warn patients and doctors about the risk of permanent blindness, even as new research found a significantly increased risk of NAION among semaglutide users

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It has been suggested that rag GTPases may control the localization of mTOR to specific vesicular membranes containing Rheb-GTP [113]