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From 5 October 2018 to 1 February 2019, 304 participants were randomly assigned to semaglutide 2.4 mg (n = 152) or placebo (n = 152), 92.8% of whom completed the trial (attended the end-of-trial safety visit)
Body fat percentage Same BMI, 2x body fat
Because of this, weekly injections of semaglutide (e.g., 0.25 mg to 2.4 mg) often produce stronger clinical outcomes in terms of weight loss and blood glucose control compared to the daily oral formulation
Worse, the risk of death was 157% higher for women with high dietary calcium intake who also took a calcium supplement
Yuan D, Sharma H, Krishnan A, Vangaveti VN, Malabu UH
