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It is a modification of the original Sermorelin peptide
Gastrointestinal symptoms are the most frequently reported adverse effects and may include: Nausea and vomiting often severe and persistent, potentially leading to dehydration and, in some cases, acute kidney injury (particularly if you have existing kidney problems) Abdominal pain or discomfort ranging from mild cramping to significant pain Diarrhoea which may be frequent and watery Loss of appetite more pronounced than usual Bloating and indigestion due to delayed gastric emptying Hypoglycaemia (low blood sugar) is another concern, particularly if you are taking other diabetes medications such as insulin or sulphonylureas
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Dr Simon Ourian, a cosmetic dermatologist in Beverly Hills, California, revealed the effect, saying: 'If you lose a lot of weight quickly, your skin gets saggy, everything from the face to the buttocks is deflated.' Patients affected by this include Nika Steward, 39, from North Carolina, who says she is 'not a fan of how I look' after a 100lb weight loss left her with excess skin
It is made from amino acids and is present in many cells, where it helps protect them from oxidative stress
Through these combined mechanisms, semaglutide users tend to lose significant weight over months of treatment
