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A composite of major kidney disease events was the primary outcome of the trial and consisted of onset of kidney failure, a 50% or greater reduction in eGFR from baseline, or kidney or CV-related mortality

Strategy 9: Smart Caffeine Management Caffeine seems like an obvious solution for fatigue, but managing it incorrectly can actually worsen energy problems over time

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Shyamali Dharmage who provided guidance for interpretation of the included studies and provided comments on the manuscript