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Espinosa De Ycaza AE, Brito JP, McCoy RG, Shao H, Singh Ospina N

Estrogen administered without progesterone stimulates the endometrial lining, increasing the risk of endometrial hyperplasia and cancer

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He suggested it after demonstrating that the glucose-lowering substance was derived from the islets (Harris)

The added glucagon receptor activity drives hepatic fat oxidation and increased energy expenditure, which dual agonists do not directly stimulate [2] [unverified]

Setting realistic expectations, attending regular follow-up appointments and making long-term lifestyle changes can help maximise the benefits of treatment while supporting lasting weight management