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Endpoints range from EEG-derived sleep-stage proportions in restrained and unrestrained animals to plasma hormone panels, behavioral pain assays and opioid-interaction protocols

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Mechanical stress can disrupt the conformation of the molecule

A recent systematic review and meta-analysis compared sleep and circadian parameters in bipolar disorders and schizophrenia [2]

These results, in addition to the conflicting results of several metabolic studies of fructose in human volunteers, suggest the relationship between fructose and hyperuricemia may be sensitive to factors aside from just the amount of ingested sugar