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USING MATHS TO IMPROVE THE SENSITIVITY OF DETECTING DRUG OR DISEASEINDUCED CHANGES Manasi Nandi 1, Miquel Serna Pascual1, Maria Volovaya1, Yujia Wu1, Rebecca D'Cruz2, Philip Aston3, Carolyn Lam1,4, Aileen Milne4, Mary McElroy4 1School and Cancer and Pharmaceutical Sciences, King's College London, Franklin Wilkins Building, 150 Stamford Street, London, U.K 2Department of Mathematics, Centre for Mathematical and Computational Biology, University of Surrey, Guildford Surrey U.K 3Lane Fox Respiratory Unit, Guys and St Thomas NHS Foundation Trust, London, U.K 4Discovery Pharmacology and Toxicology, Charles River, Edinburgh, U.K Summary: Symmetric Projection Attractor Reconstruction (SPAR) is a newly developed mathematical technique

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