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Dysregulated apoptosis signalling pathways in breast cancer cells can be reprogrammed to re-enter the apoptotic cycle, representing a critical therapeutic strategy
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The dysregulation of these diverse RCD pathways is not only extensively documented in cellular and animal models ( Table 2 ) but is also validated by transcriptomic and single-cell profiling of human clinical datasets
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It might increase the risk of developing diseases like lupus, celiac disease, and rheumatoid arthritis
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