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Non-genetic predictors of BMI loss To analyse the dependence of achieved BMI loss on non-genetic factors such as drug type, dosage and time on treatment, we fit the following model: where drugType is an indicator variable that equals 1 for individuals using semaglutide and 0 for tirzepatide, dose represents the dose in milligrams, days treat represents the total days on the relevant drug and : represents an interaction term between two or more variables
In the context of impaired glutathione metabolism, two converging factors promote PGA accumulation
Malling TH, Sigsgaard T, Brasch-Andersen C, Frischknecht L, Andersen HR, Kruse TA, et al
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Brain 146(5):18211830 Rubino DM et al (2022) Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial
