Construction of the lentiviral sgRNA library sgRNA sequences targeting each gene were selected based on previous work 67 and synthesized by Sangon Biotech, Shanghai, China
OGTT (Oral Glucose Tolerance Test): A timed test that measures your bodys response to a specific amount of sugar, used to diagnose gestational diabetes and type 2 diabetes
The 85% depletion of hepatic GSH results in a decreased GSH redox potential (E GSH )
Arch Biochem Biophys 459:295300, PMID: 17169322 Lou H, Kaplowitz N (2007) Glutathione depletion down-regulates tumor necrosis factor alpha-induced NF-kappaB activity via IkappaB kinase-dependent and -independent mechanisms
Collagens: molecular biology, diseases, and potentials for therapy
Daley, R., Maddipatla, V., Ghosh, S., Chowdhury, O., Hose, S., Zigler, J