However, TM distribution can vary with environmental conditions (Huokko et al., 2021)
A meta-analysis of seven studies including 1,757 participants with type 2 diabetes found that SGLT2 inhibitor therapy in combination with blood pressure medications (known as renin-angiotensin system blockers) was well-tolerated and resulted in greater improvement in blood pressure, glucose control, body weight, and indices of kidney function compared with the blood pressure drugs alone (Tian 2021)
The FDA still has to act on it, and formal rulemaking takes time
Extensive monitoring
What sold me completely was the lack of side effects compared to minoxidil
Nachnani JS, Bulchandani DG, Nookala A, Herndon B, Molteni A, Pandya P, Taylor R, Quinn T, Weide L, Alba LM