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Following additional FDA approvals for major adverse cardiovascular event (MACE) risk reduction in adults with established cardiovascular disease and for noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH), a tablet formulation was approved in 2025
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The manufacturer testing revealed faster degradation rates at elevated temperatures, which translated into a more conservative storage guideline
However, macronutrient profiles of what people ate remained the same before and after initiation of the drug
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