T., Kloetgen, A., MacLeod, B
After menopause, women tend to have lower activity of enzymes involved in glutathione production compared to before menopause
While glutathione supplements or treatments may improve the appearance of some people's skin, they should be used with caution and responsibility
Gut-derived metabolites may add another layer
Anraku Y, Kuwahara H, Fukusato Y, Mizoguchi A, Ishii T, Nitta K, Matsumoto Y, Toh K, Miyata K, Uchida S, Nishina K, Osada K, Itaka K, Nishiyama N, Mizusawa H, Yamasoba T, Yokota T, Kataoka K
An unbiased LC-MS-based metabolomic analysis of the small molecule metabolites in HNF4-positive HepG2 cells and HNF4-negative SNU449 cells, two widely used cell lines in the research community of liver cancer, revealed that SNU449 cells are significantly different from HepG2 cells in the abundance of 174 metabolites (Supplementary Table 1, p 1.5)