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Trends Food Sci Technol

Diabetologia 54 , 146156 (2011)

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Indeed, the thermolabile MTHFR defect and heterozygosity for CBS deficiency might increase vascular disease risk by respectively increasing the amounts of dietary folate and vitamin B 6 that are needed to prevent hyperhomocysteinemia

Until properly designed, peer-reviewed human clinical trials are completedand an FDA-regulated production pathway existsclinicians should remain cautious and avoid its clinical use in patients