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Conclusions Numerous medicinal plants and their bioactive compounds exhibit significant potential in preventing drug-induced ototoxicity through a variety of mechanisms, primarily by addressing oxidative stress and inflammation

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Methylcobalamin is a form of vitamin B12

[4] [6] The direct delivery of ascorbic acid into the bloodstream allows for supraphysiological concentrations, which could have distinct biological effects, such as pro-oxidant activity in the presence of transition metals or selective cytotoxicity against certain malignant cells, although these applications remain under investigation and are not universally accepted as standard of care

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