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A slightly lower concentration of 8-oxo-dg was found in the A-GSH group.[15] SOD-1: Superoxide is one of the main reactive oxygen species in the cell, and, as such, SOD serves a key antioxidant role
Pharmacokinetics of 2 in vivo: oral gavage Chemicals and reagents HPLC-grade water was prepared by an in-house PURELAB Option filtration system (Elga lab water solution, UK)
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Ronco C, Bellomo R, Kellum JA
As expected in Figure S20, our results showed a modest induction of cell death in normal cells, indicating a favorable safety profile for the targeting drug with minimal impact on healthy cells
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